Nexus of Nanotechnology and Cancer: Revolutionizing Cancer Treatment
Özet
Cancer is still a major health concern worldwide, and its complexity necessitates the use of a variety of therapeutic strategies. This abstract explores the complexities of cancer, explaining the many forms and underlying causes of interdisciplinary synergy between oncology and nanotechnology. It navigates through the molecular pathways and genetic abnormalities linked to the onset and development of cancer through thorough examination. It also illuminates the rapidly developing science of nanotechnology and its potential to transform cancer detection and therapy. Knowledge of cancer’s various forms, from carcinoma to sarcoma, each with its own biological origins and clinical characteristics is essential to understanding the disease. Examining the genesis of cancer reveals a complex picture that includes lifestyle variables, environmental exposures, and genetic predispositions. Deciphering these complexities offers vital information for focused treatment approaches. Nanotechnology is emerging as a paradigm-shifting force in cancer therapies, providing novel approaches to early diagnosis, imaging, and precise medication administration. Because of their specific characteristics and surface changes, nanoparticles have the most promise for getting past biological barriers, increasing the effectiveness of treatments, and reducing side effects. Furthermore, this abstract provides light on a way forward for better cancer management techniques. Integrating insights is to battle this unstoppable illness with tailored and targeted methods by fusing advances in nanotechnology with insights into cancer biology.
Referanslar
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Potente M, Mäkinen T. Vascular heterogeneity and specialization in development and disease. Nature Reviews Molecular Cell Biology; 2017;18(8): 477-94.
Ying W, Ling TM. Understanding the Psychosocial Impact of Oral Squamous Cell Carcinoma (OSCC) on Patients. Journal of Advanced Analytics in Healthcare Management; 2023; 7(1): 132-51.
Sistigu A, Musella M, Galassi C, Vitale I, De Maria R. Tuning cancer fate: tumor microenvironment's role in cancer stem cell quiescence and reawakening. Frontiers in immunology. 2020; 11: 2166.
Laconi E, Marongiu F, DeGregori J. Cancer as a disease of old age: changing mutational and microenvironmental landscapes. British journal of cancer; 2020;122(7): 943-52.
Pecorino L. Molecular biology of cancer: mechanisms, targets, and therapeutics. Oxford university press; 2021.
Rockne RC, Hawkins-Daarud A, Swanson KR, Sluka JP, Glazier JA, Macklin P, Hormuth DA, Jarrett AM, Lima EA, Oden JT, Biros G. The 2019 mathematical oncology roadmap. Physical Biology; 2019; 16(4): 041005.
Welch DR, Hurst DR. Defining the hallmarks of metastasis. Cancer research; 2019; 79(12): 3011-27.
Sethi N, Kang Y. Unravelling the complexity of metastasis—molecular understanding and targeted therapies. Nature Reviews Cancer; 2011; 11(10): 735-48.
Kiran NS, Yashaswini C, Maheshwari R, Bhattacharya S, Prajapati BG. Advances in Precision Medicine Approaches for Colorectal Cancer: From Molecular Profiling to Targeted Therapies. ACS Pharmacology & Translational Science; 2024; 7(4): 967-90.
World Health Organization. Global breast cancer initiative implementation framework: assessing, strengthening and scaling-up of services for the early detection and management of breast cancer. World Health Organization; 2023.
Bell-Wilson C. Before Pink Ribbons: Activists, Doctors, and Patients in the Fight against Breast Cancer during the Twentieth Century. California State University, Long Beach; 2019.
Bell-Wilson C. Before Pink Ribbons: Activists, Doctors, and Patients in the Fight against Breast Cancer during the Twentieth Century. California State University, Long Beach; 2019.
Roheel A, Khan A, Anwar F, Akbar Z, Akhtar MF, Imran Khan M, Sohail MF, Ahmad R. Global epidemiology of breast cancer based on risk factors: a systematic review. Frontiers in Oncology; 2023; 13: 1240098.
Armstrong N, Ryder S, Forbes C, Ross J, Quek RG. A systematic review of the international prevalence of BRCA mutation in breast cancer. Clinical epidemiology; 2019; 543-61.
Schabath MB, Cote ML. Cancer progress and priorities: lung cancer. Cancer Epidemiology, Biomarkers & Prevention; 2019; 28(10): 1563-79.
Thandra KC, Barsouk A, Saginala K, Aluru JS, Barsouk A. Epidemiology of lung cancer. Contemporary Oncology/Współczesna Onkologia; 2021; 25(1): 45-52.
Papadopoulos E, Gillen J, Moore D, Au D, Kurgan N, Klentrou P, Finelli A, Alibhai SM, Santa Mina D. High-intensity interval training or resistance training versus usual care in men with prostate cancer on active surveillance: a 3-arm feasibility randomized controlled trial. Applied Physiology, Nutrition, and Metabolism; 2021; 46(12): 1535-44.
Atasoy Ö, Erbaş O. Up to date of prostate cancer. Demiroglu Science University Florence Nightingale Journal of Medicine; 2020; 6(2): 092-102.
Keum N, Giovannucci E. Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies. Nature reviews Gastroenterology & Hepatology; 2019; 16(12): 713-32.
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Rebelatto MC. Spleen, lymph nodes, and thymus. InBoorman's Pathology of the Rat; 2018; 469-491. Academic Press.
Nigam Y, Knight J. The lymphatic system 2: structure and function of the lymphoid organs. Nursing Times; 2020; 116(11): 44-8.
McGuigan A, Kelly P, Turkington RC, Jones C, Coleman HG, McCain RS. Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes. World journal of gastroenterology; 2018; 24(43): 4846.
Güngör C, Hofmann BT, Wolters‐Eisfeld G, Bockhorn M. Pancreatic cancer. British journal of pharmacology; 2014; 171(4): 849-58.
Strauss III JF, Williams CJ. Ovarian life cycle. InYen and Jaffe's reproductive endocrinology; 2019; 167-205. Elsevier.
Karnezis AN, Cho KR, Gilks CB, Pearce CL, Huntsman DG. The disparate origins of ovarian cancers: pathogenesis and prevention strategies. Nature Reviews Cancer; 2017; 17(1): 65-74.
Cohen PA, Jhingran A, Oaknin A, Denny L. Cervical cancer. The Lancet; 2019; 393(10167): 169-82.
Halaseh SA, Halaseh S, Alali Y, Ashour ME, Alharayzah MJ, Alharayzeh MJ. A review of the etiology and epidemiology of bladder cancer: all you need to know. Cureus; 2022; 14(7).
Ifeanyi OE. A Review on Bladder Tumor Antigens. Cancer Therapy & Oncology International Journal; 2018; 9(3): 72-83.
Chidambaranathan-Reghupaty S, Fisher PB, Sarkar D. Hepatocellular carcinoma (HCC): Epidemiology, etiology and molecular classification. Advances in cancer research; 2021; 149: 1-61.
Maqbool T, Awan SJ, Malik S, Hadi F, Shehzadi S, Tariq K. In-vitro anti-proliferative, apoptotic and antioxidative activities of medicinal herb Kalonji (Nigella sativa). Current pharmaceutical biotechnology. 2019; 1;20(15):1288-308.
Anita P. Sensitivity and Specificity of Diagnostic Biomarkers in Thyroid Diseases: From circulating chemistry to molecular cytogenetics (Doctoral dissertation, BLDE (Deemed to be University)).
Singh Y, Kumari P, Giri A. Effects of Endocrine Toxicants on the Growth and Metabolism of Thyroid Glands. InEnvironmental Endocrine Toxicants; 2023; 227-258. Apple Academic Press.
Chai J. Introductory chapter: Esophagus and esophageal cancer. InEsophageal Cancer and Beyond; 2018; London, UK: IntechOpen.
Watanabe N, Shimizu M, Kochi T, Shirakami Y, Tanaka T. Esophageal carcinogenesis. Open Journal of Pathology; 2014; 4(04): 151.
Maharjan CK, Ear PH, Tran CG, Howe JR, Chandrasekharan C, Quelle DE. Pancreatic neuroendocrine tumors: molecular mechanisms and therapeutic targets. Cancers; 2021; 13(20): 5117.
Guilmette JM, Nosé V. Neoplasms of the neuroendocrine pancreas: an update in the classification, definition, and molecular genetic advances. Advances in anatomic pathology; 2019; 26(1): 13-30.
Stoyanov GS, Dzhenkov D, Ghenev P, Iliev B, Enchev Y, Tonchev AB. Cell biology of glioblastoma multiforme: from basic science to diagnosis and treatment. Medical Oncology; 2018; 35:1-0.
Wu W, Klockow JL, Zhang M, Lafortune F, Chang E, Jin L, Wu Y, Daldrup-Link HE. Glioblastoma multiforme (GBM): An overview of current therapies and mechanisms of resistance. Pharmacological research; 2021; 171: 105780.
Vodanovich DA, Choong PF. Soft-tissue sarcomas. Indian Journal of Orthopaedics; 2018; 52:35-44.
Hall F, Villalobos V, Wilky B. Future directions in soft tissue sarcoma treatment. Current problems in cancer; 2019; 43(4): 300-7.
Onugwu AL, Ugorji OL, Ufondu CA, Ihim SA, Echezona AC, Nwagwu CS, Onugwu SO, Uzondu SW, Agbo CP, Ogbonna JD, Attama AA. Nanoparticle-based delivery systems as emerging therapy in retinoblastoma: recent advances, challenges and prospects. Nanoscale Advances; 2023.
Long K, Yang Y, Lv W, Jiang K, Li Y, Lo AC, Lam WC, Zhan C, Wang W. Green light‐triggered intraocular drug release for intravenous chemotherapy of retinoblastoma. Advanced Science; 2021; 8(20): 2101754.
Ribourtout B, Zandecki M. Plasma cell morphology in multiple myeloma and related disorders. Morphologie; 2015; 99(325):38-62.
Patel P, Hussain K. Merkel cell carcinoma. Clinical and Experimental Dermatology; 2021; 46(5):814-9.
Zhang J, Walsh MF, Wu G, Edmonson MN, Gruber TA, Easton J, Hedges D, Ma X, Zhou X, Yergeau DA, Wilkinson MR. Germline mutations in predisposition genes in pediatric cancer. New England Journal of Medicine; 2015; 373(24):2336-46.
Boffetta P, Nyberg F. Contribution of environmental factors to cancer risk. British medical bulletin; 2003; 68(1): 71-94.
Gupta PC, Murti PR, Bhonsle RB. Epidemiology of cancer by tobacco products and the significance of TSNA. Tobacco-Specific N-Nitrosamines Recent Advances; 2017: 183-98.
Taylor MK, Sullivan DK, Ellerbeck EF, Gajewski BJ, Gibbs HD. Nutrition literacy predicts adherence to healthy/unhealthy diet patterns in adults with a nutrition-related chronic condition. Public health nutrition; 2019; 22(12): 2157-69.
Carballo-Fazanes A, Rico-Díaz J, Barcala-Furelos R, Rey E, Rodríguez-Fernández JE, Varela-Casal C, Abelairas-Gómez C. Physical activity habits and determinants, sedentary behaviour and lifestyle in university students. International Journal of Environmental Research and Public Health; 2020; 17(9): 3272.
Ding S, Madu CO, Lu Y. The impact of hormonal imbalances associated with obesity on the incidence of endometrial cancer in postmenopausal women. Journal of Cancer; 2020;11(18): 5456.
Smetana K, Lacina L, Szabo P, Dvořánková B, Brož P, Šedo A. Ageing as an important risk factor for cancer. Anticancer research; 2016; 36(10): 5009-17.
Fuentes E, Fuentes M, Alarcón M, Palomo I. Immune system dysfunction in the elderly. Anais da Academia Brasileira de Ciências; 2017; 89: 285-99.
Ptaschinski C, Lukacs NW. Acute and chronic inflammation induces disease pathogenesis. InMolecular Pathology; 2018; 25-43. Academic Press.
Espina C, Straif K, Friis S, Kogevinas M, Saracci R, Vainio H, Schüz J. European Code against Cancer 4th Edition: Environment, occupation and cancer. Cancer epidemiology; 2015; 39: S84-92.
Lay AA, do Nascimento CF, Horta BL, Chiavegatto Filho AD. Reproductive factors and age at natural menopause: a systematic review and meta-analysis. Maturitas; 2020; 131: 57-64.
Dalmartello M, Negri E, La Vecchia C, Scarfone G, Buonomo B, Peccatori FA, Parazzini F. Frequency of pregnancy-associated cancer: a systematic review of population-based studies. Cancers; 2020; 12(6):1356.
Sara JD, Toya T, Ahmad A, Clark MM, Gilliam WP, Lerman LO, Lerman A. Mental stress and its effects on vascular health. InMayo Clinic Proceedings; 2022; 97: (5): 951-990. Elsevier.
Jilani MH, Javed Z, Yahya T, Valero-Elizondo J, Khan SU, Kash B, Blankstein R, Virani SS, Blaha MJ, Dubey P, Hyder AA. Social determinants of health and cardiovascular disease: current state and future directions towards healthcare equity. Current Atherosclerosis Reports; 2021; 23:1-1.
Tulchinsky TH, Varavikova EA. Environmental and occupational health. The New Public Health; 2014; 471.
Balachandran DD, Miller MA, Faiz SA, Yennurajalingam S, Innominato PF. Evaluation and management of sleep and circadian rhythm disturbance in cancer. Current treatment Options in Nncology; 2021; 22:1-5.
Fardi M, Solali S, Hagh MF. Epigenetic mechanisms as a new approach in cancer treatment: An updated review. Genes & Diseases; 2018; 5(4): 304-11.
Tohme S, Simmons RL, Tsung A. Surgery for cancer: a trigger for metastases. Cancer research. 2017; 1;77(7):1548-52.
Chakroun RW, Zhang P, Lin R, Schiapparelli P, Quinones‐Hinojosa A, Cui H. Nanotherapeutic systems for local treatment of brain tumors. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology; 2018; 10(1): e1479.
Chander V, Gangenahalli G. Emerging strategies for enhancing the homing of hematopoietic stem cells to the bone marrow after transplantation. Experimental Cell Research; 2020; 390(1): 111954.
Kim A, Fall P, Wang D. Palliative care: optimizing quality of life. Journal of Osteopathic Medicine; 2005; 105(s5): 9-14.
Litter MI, Ahmad A. The world of nanotechnology. InIndustrial Applications of Nanoparticles; 2023; 1-15. CRC Press.
Stephen BJ, Suchanti S, Mishra R, Singh A. Cancer nanotechnology in medicine: a promising approach for cancer detection and diagnosis. Critical Reviews™ in Therapeutic Drug Carrier Systems; 2020; 37(4).
Salvador-Morales C, Grodzinski P. Nanotechnology tools enabling biological discovery. ACS nano; 2022; 16(4): 5062-84.
Ejigah V, Owoseni O, Bataille-Backer P, Ogundipe OD, Fisusi FA, Adesina SK. Approaches to improve macromolecule and nanoparticle accumulation in the tumor microenvironment by the enhanced permeability and retention effect. Polymers; 2022; 14(13): 2601.
Yang J, Shi Z, Liu R, Wu Y, Zhang X. Combined-therapeutic strategies synergistically potentiate glioblastoma multiforme treatment via nanotechnology. Theranostics; 2020; 10(7): 3223.
Jiang T, Gonzalez KM, Cordova LE, Lu J. Nanotechnology-enabled gene delivery for cancer and other genetic diseases. Expert Opinion on Drug Delivery; 2023; 20(4): 523-40.
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Potente M, Mäkinen T. Vascular heterogeneity and specialization in development and disease. Nature Reviews Molecular Cell Biology; 2017;18(8): 477-94.
Ying W, Ling TM. Understanding the Psychosocial Impact of Oral Squamous Cell Carcinoma (OSCC) on Patients. Journal of Advanced Analytics in Healthcare Management; 2023; 7(1): 132-51.
Sistigu A, Musella M, Galassi C, Vitale I, De Maria R. Tuning cancer fate: tumor microenvironment's role in cancer stem cell quiescence and reawakening. Frontiers in immunology. 2020; 11: 2166.
Laconi E, Marongiu F, DeGregori J. Cancer as a disease of old age: changing mutational and microenvironmental landscapes. British journal of cancer; 2020;122(7): 943-52.
Pecorino L. Molecular biology of cancer: mechanisms, targets, and therapeutics. Oxford university press; 2021.
Rockne RC, Hawkins-Daarud A, Swanson KR, Sluka JP, Glazier JA, Macklin P, Hormuth DA, Jarrett AM, Lima EA, Oden JT, Biros G. The 2019 mathematical oncology roadmap. Physical Biology; 2019; 16(4): 041005.
Welch DR, Hurst DR. Defining the hallmarks of metastasis. Cancer research; 2019; 79(12): 3011-27.
Sethi N, Kang Y. Unravelling the complexity of metastasis—molecular understanding and targeted therapies. Nature Reviews Cancer; 2011; 11(10): 735-48.
Kiran NS, Yashaswini C, Maheshwari R, Bhattacharya S, Prajapati BG. Advances in Precision Medicine Approaches for Colorectal Cancer: From Molecular Profiling to Targeted Therapies. ACS Pharmacology & Translational Science; 2024; 7(4): 967-90.
World Health Organization. Global breast cancer initiative implementation framework: assessing, strengthening and scaling-up of services for the early detection and management of breast cancer. World Health Organization; 2023.
Bell-Wilson C. Before Pink Ribbons: Activists, Doctors, and Patients in the Fight against Breast Cancer during the Twentieth Century. California State University, Long Beach; 2019.
Bell-Wilson C. Before Pink Ribbons: Activists, Doctors, and Patients in the Fight against Breast Cancer during the Twentieth Century. California State University, Long Beach; 2019.
Roheel A, Khan A, Anwar F, Akbar Z, Akhtar MF, Imran Khan M, Sohail MF, Ahmad R. Global epidemiology of breast cancer based on risk factors: a systematic review. Frontiers in Oncology; 2023; 13: 1240098.
Armstrong N, Ryder S, Forbes C, Ross J, Quek RG. A systematic review of the international prevalence of BRCA mutation in breast cancer. Clinical epidemiology; 2019; 543-61.
Schabath MB, Cote ML. Cancer progress and priorities: lung cancer. Cancer Epidemiology, Biomarkers & Prevention; 2019; 28(10): 1563-79.
Thandra KC, Barsouk A, Saginala K, Aluru JS, Barsouk A. Epidemiology of lung cancer. Contemporary Oncology/Współczesna Onkologia; 2021; 25(1): 45-52.
Papadopoulos E, Gillen J, Moore D, Au D, Kurgan N, Klentrou P, Finelli A, Alibhai SM, Santa Mina D. High-intensity interval training or resistance training versus usual care in men with prostate cancer on active surveillance: a 3-arm feasibility randomized controlled trial. Applied Physiology, Nutrition, and Metabolism; 2021; 46(12): 1535-44.
Atasoy Ö, Erbaş O. Up to date of prostate cancer. Demiroglu Science University Florence Nightingale Journal of Medicine; 2020; 6(2): 092-102.
Keum N, Giovannucci E. Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies. Nature reviews Gastroenterology & Hepatology; 2019; 16(12): 713-32.
Granados-Romero JJ, Valderrama-Treviño AI, Contreras-Flores EH, Barrera-Mera B, Herrera Enríquez M, Uriarte-Ruíz K, Ceballos-Villalba JC, Estrada-Mata AG, Alvarado Rodríguez C, Arauz-Peña G. Colorectal cancer: a review. International Journal of Research in Medical Sciences; 2017; 5(11): 4667.
Labani S, Asthana S, Rathore K, Sardana K. Incidence of melanoma and nonmelanoma skin cancers in Indian and the global regions. Journal of cancer research and therapeutics; 2021; 17(4): 906-11.
Asna N, Livoff A, Batash R, Debbi R, Schaffer P, Rivkind T, Schaffer M. Radiation therapy and immunotherapy—a potential combination in cancer treatment. Current Oncology; 2018; 25(5): 454-60.
Rebelatto MC. Spleen, lymph nodes, and thymus. InBoorman's Pathology of the Rat; 2018; 469-491. Academic Press.
Nigam Y, Knight J. The lymphatic system 2: structure and function of the lymphoid organs. Nursing Times; 2020; 116(11): 44-8.
McGuigan A, Kelly P, Turkington RC, Jones C, Coleman HG, McCain RS. Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes. World journal of gastroenterology; 2018; 24(43): 4846.
Güngör C, Hofmann BT, Wolters‐Eisfeld G, Bockhorn M. Pancreatic cancer. British journal of pharmacology; 2014; 171(4): 849-58.
Strauss III JF, Williams CJ. Ovarian life cycle. InYen and Jaffe's reproductive endocrinology; 2019; 167-205. Elsevier.
Karnezis AN, Cho KR, Gilks CB, Pearce CL, Huntsman DG. The disparate origins of ovarian cancers: pathogenesis and prevention strategies. Nature Reviews Cancer; 2017; 17(1): 65-74.
Cohen PA, Jhingran A, Oaknin A, Denny L. Cervical cancer. The Lancet; 2019; 393(10167): 169-82.
Halaseh SA, Halaseh S, Alali Y, Ashour ME, Alharayzah MJ, Alharayzeh MJ. A review of the etiology and epidemiology of bladder cancer: all you need to know. Cureus; 2022; 14(7).
Ifeanyi OE. A Review on Bladder Tumor Antigens. Cancer Therapy & Oncology International Journal; 2018; 9(3): 72-83.
Chidambaranathan-Reghupaty S, Fisher PB, Sarkar D. Hepatocellular carcinoma (HCC): Epidemiology, etiology and molecular classification. Advances in cancer research; 2021; 149: 1-61.
Maqbool T, Awan SJ, Malik S, Hadi F, Shehzadi S, Tariq K. In-vitro anti-proliferative, apoptotic and antioxidative activities of medicinal herb Kalonji (Nigella sativa). Current pharmaceutical biotechnology. 2019; 1;20(15):1288-308.
Anita P. Sensitivity and Specificity of Diagnostic Biomarkers in Thyroid Diseases: From circulating chemistry to molecular cytogenetics (Doctoral dissertation, BLDE (Deemed to be University)).
Singh Y, Kumari P, Giri A. Effects of Endocrine Toxicants on the Growth and Metabolism of Thyroid Glands. InEnvironmental Endocrine Toxicants; 2023; 227-258. Apple Academic Press.
Chai J. Introductory chapter: Esophagus and esophageal cancer. InEsophageal Cancer and Beyond; 2018; London, UK: IntechOpen.
Watanabe N, Shimizu M, Kochi T, Shirakami Y, Tanaka T. Esophageal carcinogenesis. Open Journal of Pathology; 2014; 4(04): 151.
Maharjan CK, Ear PH, Tran CG, Howe JR, Chandrasekharan C, Quelle DE. Pancreatic neuroendocrine tumors: molecular mechanisms and therapeutic targets. Cancers; 2021; 13(20): 5117.
Guilmette JM, Nosé V. Neoplasms of the neuroendocrine pancreas: an update in the classification, definition, and molecular genetic advances. Advances in anatomic pathology; 2019; 26(1): 13-30.
Stoyanov GS, Dzhenkov D, Ghenev P, Iliev B, Enchev Y, Tonchev AB. Cell biology of glioblastoma multiforme: from basic science to diagnosis and treatment. Medical Oncology; 2018; 35:1-0.
Wu W, Klockow JL, Zhang M, Lafortune F, Chang E, Jin L, Wu Y, Daldrup-Link HE. Glioblastoma multiforme (GBM): An overview of current therapies and mechanisms of resistance. Pharmacological research; 2021; 171: 105780.
Vodanovich DA, Choong PF. Soft-tissue sarcomas. Indian Journal of Orthopaedics; 2018; 52:35-44.
Hall F, Villalobos V, Wilky B. Future directions in soft tissue sarcoma treatment. Current problems in cancer; 2019; 43(4): 300-7.
Onugwu AL, Ugorji OL, Ufondu CA, Ihim SA, Echezona AC, Nwagwu CS, Onugwu SO, Uzondu SW, Agbo CP, Ogbonna JD, Attama AA. Nanoparticle-based delivery systems as emerging therapy in retinoblastoma: recent advances, challenges and prospects. Nanoscale Advances; 2023.
Long K, Yang Y, Lv W, Jiang K, Li Y, Lo AC, Lam WC, Zhan C, Wang W. Green light‐triggered intraocular drug release for intravenous chemotherapy of retinoblastoma. Advanced Science; 2021; 8(20): 2101754.
Ribourtout B, Zandecki M. Plasma cell morphology in multiple myeloma and related disorders. Morphologie; 2015; 99(325):38-62.
Patel P, Hussain K. Merkel cell carcinoma. Clinical and Experimental Dermatology; 2021; 46(5):814-9.
Zhang J, Walsh MF, Wu G, Edmonson MN, Gruber TA, Easton J, Hedges D, Ma X, Zhou X, Yergeau DA, Wilkinson MR. Germline mutations in predisposition genes in pediatric cancer. New England Journal of Medicine; 2015; 373(24):2336-46.
Boffetta P, Nyberg F. Contribution of environmental factors to cancer risk. British medical bulletin; 2003; 68(1): 71-94.
Gupta PC, Murti PR, Bhonsle RB. Epidemiology of cancer by tobacco products and the significance of TSNA. Tobacco-Specific N-Nitrosamines Recent Advances; 2017: 183-98.
Taylor MK, Sullivan DK, Ellerbeck EF, Gajewski BJ, Gibbs HD. Nutrition literacy predicts adherence to healthy/unhealthy diet patterns in adults with a nutrition-related chronic condition. Public health nutrition; 2019; 22(12): 2157-69.
Carballo-Fazanes A, Rico-Díaz J, Barcala-Furelos R, Rey E, Rodríguez-Fernández JE, Varela-Casal C, Abelairas-Gómez C. Physical activity habits and determinants, sedentary behaviour and lifestyle in university students. International Journal of Environmental Research and Public Health; 2020; 17(9): 3272.
Ding S, Madu CO, Lu Y. The impact of hormonal imbalances associated with obesity on the incidence of endometrial cancer in postmenopausal women. Journal of Cancer; 2020;11(18): 5456.
Smetana K, Lacina L, Szabo P, Dvořánková B, Brož P, Šedo A. Ageing as an important risk factor for cancer. Anticancer research; 2016; 36(10): 5009-17.
Fuentes E, Fuentes M, Alarcón M, Palomo I. Immune system dysfunction in the elderly. Anais da Academia Brasileira de Ciências; 2017; 89: 285-99.
Ptaschinski C, Lukacs NW. Acute and chronic inflammation induces disease pathogenesis. InMolecular Pathology; 2018; 25-43. Academic Press.
Espina C, Straif K, Friis S, Kogevinas M, Saracci R, Vainio H, Schüz J. European Code against Cancer 4th Edition: Environment, occupation and cancer. Cancer epidemiology; 2015; 39: S84-92.
Lay AA, do Nascimento CF, Horta BL, Chiavegatto Filho AD. Reproductive factors and age at natural menopause: a systematic review and meta-analysis. Maturitas; 2020; 131: 57-64.
Dalmartello M, Negri E, La Vecchia C, Scarfone G, Buonomo B, Peccatori FA, Parazzini F. Frequency of pregnancy-associated cancer: a systematic review of population-based studies. Cancers; 2020; 12(6):1356.
Sara JD, Toya T, Ahmad A, Clark MM, Gilliam WP, Lerman LO, Lerman A. Mental stress and its effects on vascular health. InMayo Clinic Proceedings; 2022; 97: (5): 951-990. Elsevier.
Jilani MH, Javed Z, Yahya T, Valero-Elizondo J, Khan SU, Kash B, Blankstein R, Virani SS, Blaha MJ, Dubey P, Hyder AA. Social determinants of health and cardiovascular disease: current state and future directions towards healthcare equity. Current Atherosclerosis Reports; 2021; 23:1-1.
Tulchinsky TH, Varavikova EA. Environmental and occupational health. The New Public Health; 2014; 471.
Balachandran DD, Miller MA, Faiz SA, Yennurajalingam S, Innominato PF. Evaluation and management of sleep and circadian rhythm disturbance in cancer. Current treatment Options in Nncology; 2021; 22:1-5.
Fardi M, Solali S, Hagh MF. Epigenetic mechanisms as a new approach in cancer treatment: An updated review. Genes & Diseases; 2018; 5(4): 304-11.
Tohme S, Simmons RL, Tsung A. Surgery for cancer: a trigger for metastases. Cancer research. 2017; 1;77(7):1548-52.
Chakroun RW, Zhang P, Lin R, Schiapparelli P, Quinones‐Hinojosa A, Cui H. Nanotherapeutic systems for local treatment of brain tumors. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology; 2018; 10(1): e1479.
Chander V, Gangenahalli G. Emerging strategies for enhancing the homing of hematopoietic stem cells to the bone marrow after transplantation. Experimental Cell Research; 2020; 390(1): 111954.
Kim A, Fall P, Wang D. Palliative care: optimizing quality of life. Journal of Osteopathic Medicine; 2005; 105(s5): 9-14.
Litter MI, Ahmad A. The world of nanotechnology. InIndustrial Applications of Nanoparticles; 2023; 1-15. CRC Press.
Stephen BJ, Suchanti S, Mishra R, Singh A. Cancer nanotechnology in medicine: a promising approach for cancer detection and diagnosis. Critical Reviews™ in Therapeutic Drug Carrier Systems; 2020; 37(4).
Salvador-Morales C, Grodzinski P. Nanotechnology tools enabling biological discovery. ACS nano; 2022; 16(4): 5062-84.
Ejigah V, Owoseni O, Bataille-Backer P, Ogundipe OD, Fisusi FA, Adesina SK. Approaches to improve macromolecule and nanoparticle accumulation in the tumor microenvironment by the enhanced permeability and retention effect. Polymers; 2022; 14(13): 2601.
Yang J, Shi Z, Liu R, Wu Y, Zhang X. Combined-therapeutic strategies synergistically potentiate glioblastoma multiforme treatment via nanotechnology. Theranostics; 2020; 10(7): 3223.
Jiang T, Gonzalez KM, Cordova LE, Lu J. Nanotechnology-enabled gene delivery for cancer and other genetic diseases. Expert Opinion on Drug Delivery; 2023; 20(4): 523-40.
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Sayfalar
203-225
Gelecek
14 Şubat 2025
Telif Hakkı (c) 2025 Akademisyen Yayınevi Kitap DOI Portalı
